Nineteen of the Russian's 21 championships have been earned on hardcourt
A comeback the Russian player claimed his initial title for nearly 30 months with victory over Corentin Moutet in the tournament final.
Medvedev, a former world number one, has experienced a challenging season, winning just one win at the Grand Slams and suffering a meltdown at the US Open.
The player's varied form on the professional circuit - and difficulties with his serving in especial - caused him dropping out of the world's top 10 and eventually parting ways with former mentor Gilles Cervara.
Currently collaborating with Thomas Johansson and Goetzke, he has consistently improved in the last few weeks - climaxing in a closely contested competitive triumph over Frenchman Moutet.
This marks Medvedev's initial title after the Rome competition and first on a hardcourt since that period of that year.
The win also signifies he has achieved 21 titles at 21 different competitions.
"It's the first time I'm at a event with my both daughters together, so to secure a title is especially meaningful," said world number 14 Daniil Medvedev.
"This championship is in tribute of my younger daughter Victoria, because the maiden victory I achieved when my child Alisa was born was for her."
The tennis star, the 2021 US Open champion, had failed in his last six title deciders, featuring in that event previously this season.
His defensive strategy and frequent reactions on the tennis court had led commentators to wonder if his capacity to perform at the top level was concluded.
However the player has made changes in the past month, making an effort to approach the net and compete aggressively, supported by an better serve.
He fought back from a disadvantage in the opening set against the challenging Frenchman, taking 4 of the last five points to go ahead.
Both players traded break points in the following set before the challenger, bidding for his first ATP Tour victory, gained dominance to push for a third set.
He rescued four early-game break points in a competitive third set before Medvedev won the break to fifteen to close out the victory.
Appropriately, he earned victory with a rally at the front of the court, with the Frenchman unable to control a volley after two hours and 38 minutes.
